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KMID : 0360319920240010140
Journal of Korean Cancer Research Association
1992 Volume.24 No. 1 p.140 ~ p.148
A Clinical Study of 5-Year Survival Rate of Stomach Cancer According to Postoperative Anticancer Chemotherapy



Abstract
The gastric cancer is the most common malignancy in Korean and the number of them is seemed to be increasing every year. We could made a clinical analysis of 492 cases of the gastric cancer which were operated in the Dept, of Surgery, Kyung Hee
University Hospital from January, 1979 to April, 1986.
@ES The results were as follows:
@EN 1) The age was from 17 years to 78 years old. Peak age incidence was 6th decade(28.9%), the mean age was 52.6 years and the ratio of male to female was 1.8:1.
2) Clinical symptoms, in order of frequency, were epigastric pain(40.2%), weight loss(35.0%), nausea(16.3%) and vomiting(15.4%). On physical examination, epigastric tenderness(39.0%) and palpable abdominal mass(18.3%) were common.
3) Preoperatively, 376 cases(76.4%) were seemed to be resectable and 42 cases(8.5%) were early gastric cancer, But postoperatively, 399 cases(81.1%) were curatively resectable and 90 cases(18.3%) wer early gastric cancer.
4) Distribution of the primary lesion, in order of frequency, wer antrum(71.5%), body(20.5%) and cardia-fudus(8.0%).
5) In TMN staging of the lesion, stage I was 60 cases(12.2%), stage III 64 cases(13.0%), stage III 242 cases(49.2%) and stage IV 126 cases(25.6%).
6) The operative procedure were radical subtotal gastrectomy(69.1%), total gastrectomy(12.0%), palliative resection(4.9%), bypass operation(10.4%) and biopsy only(3.6%).
7) The postoperative complications were developed in 124 cases(15.2%) and common complications were pulmonary complications, wound infection, intraabdominal abscess and enterocutaneous fistula, in order of frequency.
8) The ovrall operative mortality was 2.4%(12/492).
9) The overall 5-year survival rate of all gastric cancer patients was 53.8% and stage I was 94.9%, stage II 81.4%, stage III 52.1% and stage IV 14.9%.
10) IN stage II, 5-year survival rate was 75.9% in none chemotherapy group, 71.4% in MFC group and 91.3% in FAM group(statistically insignificant). In stage III, 5-year survival rate was 37% in none chemotherapy group, 45.9% in MFC group and
60.3%
in
FAM group(statistically significant). In stage IV, statistical significancy was showed between none chemotherapy group and FAM group(8.5%, vs, 23.5%).
KEYWORD
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